Document Detail

Influence of ACTH on activity of some granulocytic proteases in patients with multiple sclerosis.
MedLine Citation:
PMID:  224833     Owner:  NLM     Status:  MEDLINE    
The effect of treatment with ACTH on activity of granulocytic acid and neutral proteases in patients suffering from multiple sclerosis was studied. Protease activity was distinctly higher in granulocytes from patients. ACTH normalized the activities investigated in patients with exacerbating course multiple sclerosis, but had no influence on hydrolases in the progressive form of the disease.
J Czernicki; H Tchórzewski; H Chmielewski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archivum immunologiae et therapiae experimentalis     Volume:  27     ISSN:  0004-069X     ISO Abbreviation:  Arch. Immunol. Ther. Exp. (Warsz.)     Publication Date:  1979  
Date Detail:
Created Date:  1979-10-17     Completed Date:  1979-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114365     Medline TA:  Arch Immunol Ther Exp (Warsz)     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  345-9     Citation Subset:  IM    
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MeSH Terms
Adrenocorticotropic Hormone / pharmacology*,  therapeutic use
Granulocytes / enzymology*
Lysosomes / enzymology
Multiple Sclerosis / blood,  drug therapy,  enzymology*
Peptide Hydrolases / metabolism*
Reg. No./Substance:
9002-60-2/Adrenocorticotropic Hormone; EC 3.4.-/Peptide Hydrolases

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