| Inflection point of ascending aortic waveform is a powerful predictor of restenosis after percutaneous transluminal coronary angioplasty. | |
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MedLine Citation:
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PMID: 12219879 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although it was reported that the pulsatility of ascending aortic pressure is closely related to restenosis after percutaneous transluminal coronary angioplasty (PTCA), it is not known whether the reflection period of ascending aortic pressure can predict restenosis after PTCA. The purpose of this study was to evaluate whether reflection in the arterial system can be used to predict restenosis after PTCA. METHODS: We used the inflection point as the reflection period index and measured the coronary artery diameter, aortic pressure, and inflection time before PTCA. We defined the inflection time as the time interval from the initiation of systolic pressure waveform to the inflection point. We prospectively investigated the effect of inflection time in relation to the subsequent risk of restenosis after PTCA in patients with coronary artery disease. RESULTS: Crude cumulative incidence rates of restenosis were 74.1% for the lowest, 33.3% for the middle, and 26.1% for the highest tertile of inflection point levels. After adjustments for age, gender, smoking habits, hypertension, type 2 diabetes, hypercholesterolemia, old myocardial infarction, vessel location, post-minimal lumen diameter, heart rate, and ejection fraction, the odds ratio of restenosis was 6.99 (95% confidence interval, 1.54 to 31.7) for the lowest tertile of the inflection time level compared with the highest tertile level. CONCLUSIONS: Inflection time is a powerful predictor of restenosis after PTCA. |
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Authors:
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Hiroyasu Ueda; Yasunori Nakayama; Kei Tsumura; Kiyomichi Yoshimaru; Tomoshige Hayashi; Junichi Yoshikawa |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: American journal of hypertension Volume: 15 ISSN: 0895-7061 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-10 Completed Date: 2003-04-30 Revised Date: 2009-02-24 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 823-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Ishikiriseiki Hospital, Higashiosaka-City, Osaka, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary* Aorta / physiopathology* Coronary Artery Disease / therapy* Coronary Restenosis / physiopathology* Female Humans Male Middle Aged Multivariate Analysis Prospective Studies Pulsatile Flow / physiology* Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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