Document Detail

Inflammatory syndrome in patients on hemodialysis.
MedLine Citation:
PMID:  17130274     Owner:  NLM     Status:  MEDLINE    
Mortality is markedly elevated in hemodialysis (HD) patients. Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality risk. The causes of inflammation are multifactorial and include patient-related factors, such as underlying disease, comorbidity, oxidative stress, infections, obesity, and genetic or immunologic factors, or on the other side, HD-related factors, mainly depending on the membrane biocompatibility and dialysate quality. The adequate knowledge of these causes and their prevention or treatment if possible may contribute to improving the inflammatory state of patients who are on HD and possibly their mortality.
Rosa Jofré; Patrocinio Rodriguez-Benitez; Juan M López-Gómez; Rafael Pérez-Garcia
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American Society of Nephrology : JASN     Volume:  17     ISSN:  1046-6673     ISO Abbreviation:  J. Am. Soc. Nephrol.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-28     Completed Date:  2007-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013836     Medline TA:  J Am Soc Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S274-80     Citation Subset:  IM    
Servicio de Nephrología, Hospital Gregorio Marañón, Madrid, Spain.
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MeSH Terms
Inflammation / etiology*,  prevention & control
Kidney Failure, Chronic / therapy
Renal Dialysis / adverse effects*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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