Document Detail


Inflammatory state of Type II diabetic patients with chronic ulcers in response to herbal treatment.
MedLine Citation:
PMID:  22463944     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Type II diabetic patients easily develop ulcers over their feet which heal with great difficulties and not infrequently, end up in amputations. In the quest for innovative means to avoid amputation, herbal medicine has been used in China to heal ulcers. METHOD: A randomized placebo controlled clinical trial involving 80 patients was conducted to test whether a herbal formula taken orally could help to preserve the ulcerated leg. Other parameters measured included granulation maturation time, skin temperature and circulation, and tumor necrosis factor alpha (TNF-α). RESULTS: showed a 85% limb rescue with the herbal treatment group showing superiority over placebo group. TNF-α decline was observed with gradual ulcer healing and the herbal supplement group showed a more impressive decline (p=0.037).
Authors:
P C Leung; S Y Pang; E L Y Wong; K F Cheng
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-29
Journal Detail:
Title:  Foot (Edinburgh, Scotland)     Volume:  -     ISSN:  1532-2963     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-4-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9109564     Medline TA:  Foot (Edinb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong; Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong.
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