Document Detail

Inflammatory pseudotumour (plasma cell granuloma) arising in the maxillary sinus.
MedLine Citation:
PMID:  15966706     Owner:  NLM     Status:  MEDLINE    
CONCLUSIONS: Inflammatory pseudotumours in the maxillary sinus may present as malignant tumours and manifest locally aggressive features characteristic of such tumours. Despite their locally destructive features, they pursue a benign course after local excision. OBJECTIVE: Inflammatory pseudotumour (plasma cell granuloma) is an uncommon non-neoplastic lesion comprising a proliferation of spindle myofibroblasts and chronic inflammatory cells. Despite its benign histopathological nature, it may exhibit aggressive behaviour that is yet to be characterized in the head and neck area. MATERIAL AND METHODS: We present the cases of two adult patients with inflammatory pseudotumour arising from the maxillary sinus. Immunohistochemistry and polymerase chain reaction for immunoglobulin from tissue sections were performed to confirm the polyclonality of the infiltrating plasma cells. RESULTS: CT and MRI disclosed expansive soft masses eroding surrounding soft and bony tissues. Histopathologically, the lesions were unencapsulated and composed of numerous plasma cells, histiocytes and spindle cells with minimal nuclear pleomorphism.
Shin-Ichiro Maruya; Hidekachi Kurotaki; Toshimitsu Hashimoto; Shuji Ohta; Hideichi Shinkawa; Soroku Yagihashi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  125     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-06-21     Completed Date:  2005-07-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  322-7     Citation Subset:  IM    
Department of Pathology, Hirosaki University, Zaifucho, Hirosaki, Japan.
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MeSH Terms
Blood Sedimentation
C-Reactive Protein / analysis
Granuloma, Plasma Cell / diagnosis*,  metabolism,  therapy
Immunoglobulin Light Chains / metabolism
Magnetic Resonance Imaging
Maxillary Sinus Neoplasms / diagnosis*,  metabolism,  therapy
Tomography, X-Ray Computed
Reg. No./Substance:
0/Immunoglobulin Light Chains; 9007-41-4/C-Reactive Protein

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