Document Detail


Inflammatory pseudotumor (plasma cell granuloma) of the heart. Report of two cases and literature review.
MedLine Citation:
PMID:  8651856     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report pathologic findings in two patients with inflammatory pseudotumor of the heart. The first patient was a 15-year-old-boy who died suddenly and unexpectedly of myocardial ischemia caused by an angiocentric inflammatory pseudotumor affecting all of the major coronary arteries and some of their branches. Inflammatory pseudotumor was also centered around some intrasplenic arteries. The second patient was a 5-month-old girl who had subtotal resection of a mass in the right atrial free wall. Her inflammatory pseudotumor was confined to the myocardium and showed no angiocentricity. The patient is doing well 22 months after surgery. Inflammatory pseudotumor is a benign inflammatory response evoked by an unknown agent(s). In both patients, the inflammatory cells comprised a mixture of B and T lymphocytes. Among B cells, a mixture of kappa and lambda plasma cells was evident. A moderate number of tissue macrophages was also observed. The process is usually self-limited but may cause death if vital structures are involved.
Authors:
A G Rose; S McCormick; K Cooper; J L Titus
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  120     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-07-24     Completed Date:  1996-07-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  549-54     Citation Subset:  AIM; IM    
Affiliation:
Jesse E. Edwards Registry of Cardiovascular Disease, United Hospital, St Paul, MN 55102, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
B-Lymphocytes / pathology
Biological Markers / analysis
Coronary Vessels / metabolism,  pathology
Fatal Outcome
Female
Granuloma, Plasma Cell / metabolism,  pathology*
Heart Diseases / metabolism,  pathology*
Humans
Immunohistochemistry
Infant
Male
Spleen / metabolism,  pathology
T-Lymphocytes / pathology
Tunica Intima / metabolism,  pathology
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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