Document Detail


Inflammatory pseudohistoplasmosis.
MedLine Citation:
PMID:  4051378     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients with multifocal choroiditis, presumed ocular histoplasmosis syndrome (POHS) is often diagnosed. However, POHS typically is not associated with inflammatory activity in the ocular media. A group of patients had a pattern of multifocal choroidal spots reminiscent of POHS with active signs of inflammation in the anterior and vitreous chambers. Of the 28 patients, 43% were black. In addition to inflammation, many patients had peripapillary atrophy (39%) or diskiform macular scars (32%). Of those with diskiform scars, 33% were black. Systemically, 32% of the patients were presumed to have sarcoidosis; 29%, tuberculosis; 11%, syphilis; and 28%, no etiology. In some cases, treatment of the underlying disease resulted in improvement of the ocular findings. Inflammatory pseudohistoplasmosis syndrome appears to be a nonspecific response to a number of uveitic syndromes, including sarcoidosis, tuberculosis, and syphilis.
Authors:
T A Deutsch; H H Tessler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of ophthalmology     Volume:  17     ISSN:  0003-4886     ISO Abbreviation:  Ann Ophthalmol     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-21     Completed Date:  1985-11-21     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0210137     Medline TA:  Ann Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  461-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
African Continental Ancestry Group
Aged
Behcet Syndrome / pathology
Chorioretinitis / pathology
Choroiditis / etiology*,  pathology
Diagnosis, Differential
European Continental Ancestry Group
Female
Histoplasmosis / pathology*
Humans
Male
Middle Aged
Sarcoidosis / complications,  diagnosis
Syphilis / complications,  diagnosis
Tuberculosis / complications,  diagnosis
Uveomeningoencephalitic Syndrome / pathology
Grant Support
ID/Acronym/Agency:
EY1792/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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