| Inflammatory mediators involved in the progression of metabolic syndrome. | |
| | |
MedLine Citation:
|
PMID: 22389088 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Metabolic syndrome consists of a constellation of risk factors including primarily abdominal obesity, hyperglycemia, low high-density lipoproteins, hypertriglyceridemia, and hypertension. It encompasses Type 2 diabetes mellitus, dyslipidemia, atherosclerosis, hypertension, hepatic steatosis and so on. Recent studies enhanced our understanding of molecular mechanisms of the inflammatory progression in metabolic syndrome. Especially, a number of inflammatory mediators including cytokines, adipokines and eicosanoids induced inflammatory responses that eventually lead to the development of metabolic syndrome. Therefore, measuring the levels of certain inflammatory molecules might provide useful information on the inflammatory state, which may have clinical importance and significance. The selective intervention of some of these molecules might have the therapeutic potential to modulate inflammatory responses, and thereby could alter disease progression. In this review, we would briefly summarize the recent studies on classical and newer inflammatory mediators in the pathogenesis of different human and experimental metabolic syndrome. Copyright © 2012 John Wiley & Sons, Ltd. |
| | |
Authors:
|
Kuifen Ma; Xi Jin; Xingguang Liang; Qingwei Zhao; Xingguo Zhang |
Related Documents
:
|
19583928 - Methodology of pharmacodynamic evaluation on chinese herbal medicine based on syndrome ... 20220348 - The athlete and high altitude. 8400858 - Congenital myasthenic syndromes. 19414148 - Hamartomatous polyposis syndromes. 36978 - Prolactin-secreting adenoma as part of the multiple endocrine neoplasia--type i (men-i)... 8435798 - Crystalglobulinemia syndrome. a manifestation of multiple myeloma. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-3-2 |
Journal Detail:
|
Title: Diabetes/metabolism research and reviews Volume: - ISSN: 1520-7560 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-3-5 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883450 Medline TA: Diabetes Metab Res Rev Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 John Wiley & Sons, Ltd. |
Affiliation:
|
The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003. jancemkf@163.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Residual effects of ecstasy (3,4-methylenedioxymethamphetamine) on low level visual processes.
Next Document: Clinical, histopathologic, and genetic features of pediatric primary myelofibrosis-An entity differe...