| Inflammatory manifestations at colonoscopy in patients with colonic diverticular disease. | |
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MedLine Citation:
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PMID: 21133960 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aliment Pharmacol Ther 2011; 33: 358-365 SUMMARY: Background Ulcerative colitis with diverticulosis (UCD), segmental colitis associated with diverticulosis (SCAD) and acute uncomplicated diverticulitis (AUD) may affect the same colonic regions, but the real incidence of these entities in clinical practice is unknown. Aim To assess the incidence and the endoscopic findings of UCD, SCAD and AUD. Methods From January 2004 to June 2009, 8525 consecutive colonoscopies were performed. Diagnosis of the diseases was based on specific endoscopic and histological (UCD and SCAD), and on endoscopic and radiological (AUD) patterns. Results Ulcerative colitis with diverticulosis was diagnosed in 25 patients (0.3%), SCAD was diagnosed in 129 patients (2%) and AUD was diagnosed in 130 patients (2%). In UCD, the inflammation in colonic area harbouring diverticula always affects the overall colonic mucosa in all cases, involving also diverticular orifices. The endoscopic characteristic of SCAD is that inflammation is mainly detected within the inter-diverticular mucosa without involvement of the diverticular orifices. In AUD, the inflammation affects primarily diverticular orifice and peri-diverticular mucosa. Conclusions In clinical practice, the incidence of mucosal inflammation in the presence of colonic diverticular disease is low and endoscopy is the mainstay of differential diagnosis. |
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Authors:
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A Tursi; W Elisei; G M Giorgetti; F Aiello; G Brandimarte |
Publication Detail:
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Type: Journal Article Date: 2010-12-07 |
Journal Detail:
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Title: Alimentary pharmacology & therapeutics Volume: 33 ISSN: 1365-2036 ISO Abbreviation: Aliment. Pharmacol. Ther. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8707234 Medline TA: Aliment Pharmacol Ther Country: England |
Other Details:
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Languages: eng Pagination: 358-65 Citation Subset: IM |
Copyright Information:
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© 2010 Blackwell Publishing Ltd. |
Affiliation:
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Servizio di Gastroenterologia Territoriale, ASL BAT, Andria, Bari, Italy. U.O.C. di Gastroenterologia, ASL Roma H, Albano Laziale, Rome, Italy. U.O.D. di Endoscopia Digestiva e Nutrizionale, Ospedale "S. Eugenio", Rome, Italy. Dipartimento di Scienze Matematiche e Statistiche, Università di Palermo, Palermo, Italy. U.O.S. di Gastroenterologia, Ospedale "Cristo Re", Rome, Italy. |
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