| Inflammatory arthritis following ustekinumab treatment for psoriasis: a report of two cases. | |
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MedLine Citation:
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PMID: 23278559 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Psoriasis is a chronic inflammatory skin condition, characterized by T-helper (Th) 1 and Th17 cell activation. Ustekinumab is a fully human immunoglobulin G1κ monoclonal antibody that targets the common p40 subunit that is shared by both interleukin (IL)-12 and IL-23, consequently inhibiting T-cell differentiation along both Th1 and Th17 pathways. This is a report of two patients who developed psoriatic arthritis during ustekinumab treatment for psoriasis. Neither patient had a personal or family history of arthritis. |
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Authors:
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A de Souza; T Ali-Shaw; S M Reddy; D Fiorentino; B E Strober |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 168 ISSN: 1365-2133 ISO Abbreviation: Br. J. Dermatol. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-01-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 210-2 Citation Subset: IM |
Copyright Information:
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© 2012 The Authors. BJD © 2012 British Association of Dermatologists. |
Affiliation:
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Department of Dermatology, New York University Hospital for Joint Disease, New York University School of Medicine, New York, NY, U.S.A. Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, U.S.A. Department of Dermatology, University of Connecticut School of Medicine, Farmington, CT, U.S.A. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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