Document Detail

Inflammatory abdominal aortic aneurysm and the associated T-cell reaction: a case study.
MedLine Citation:
PMID:  1538516     Owner:  NLM     Status:  MEDLINE    
The immune response associated with an inflammatory abdominal aortic aneurysm was studied by determining the phenotypes of lymphocytes in the peripheral blood, the aortic aneurysm wall, and the perianeurysmal tissue. Increased numbers of activated T cells were found in all three areas. After aneurysm repair, peripheral blood analysis demonstrated normalization of the T-cell subsets. These data suggest that inflammatory abdominal aortic aneurysm is associated with a measurable immune response in peripheral blood with elevation of the same subset of inflammatory cells (CD4) as detected in abdominal aortic aneurysm tissue, and the immune response regresses after aneurysm repair.
J Lieberman; J S Scheib; P B Googe; A T Ichiki; M H Goldman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  15     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-03-27     Completed Date:  1992-03-27     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  569-72     Citation Subset:  IM    
Department of Surgery, University of Tennessee Medical Center, Knoxville 37920.
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MeSH Terms
Aorta, Abdominal
Aortic Aneurysm / blood,  immunology*
Aortitis / blood,  immunology*
Immunity, Cellular
Lymphocyte Subsets / physiology*
Comment In:
J Vasc Surg. 1992 Oct;16(4):662-3   [PMID:  1404686 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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