| Inflammatory Myopathy. | |
| | |
MedLine Citation:
|
PMID: 11096714 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Patients with polymyositis or dermatomyositis should be treated with prednisone (approximately 1 mg/kg/d) for an initial period of 4 to 6 weeks. Once improvement occurs, the dose should be tapered and converted to an alternate-day regimen, which should be continued for at least 12 months. Methotrexate or azathioprine should be administered concomitantly to patients in whom there is inadequate control. The early introduction of one of these drugs allows more rapid reduction in the dose of prednisone and helps to avert serious side effects. Intravenous immunoglobulin therapy is indicated for patients who have immunodeficiency, who are unable to tolerate immu-nosuppressive drugs, whose conditions are deteriorating, or who have severe relapses. Cyclosporine or cyclophosphamide may be effective for resistant disease. Patients with inclusion body myositis should undergo a 3- to 6-month trial of prednisone, alone or in combination with methotrexate or azathioprine. Maintenance doses of these drugs should be continued if the patient's condition improves or stabilizes. |
| | |
Authors:
|
Mastaglia; Phillips; Zilko |
Related Documents
:
|
21196094 - Effective dose range for dental cone beam computed tomography scanners. 18311044 - A case report of rheumatoid arthritis complicated with rapidly progressive interstitial... 10669204 - High-dose intravenous immunoglobulin therapy in juvenile myasthenia gravis. 20010324 - Infliximab stability after reconstitution, dilution, and storage under refrigeration. 2117204 - European multicenter trials of curosurf for treatment of neonatal respiratory distress ... 10744344 - Pharmacokinetics of several subcutaneous doses of erythropoietin: potential implication... |
Publication Detail:
|
Type: JOURNAL ARTICLE |
Journal Detail:
|
Title: Current treatment options in neurology Volume: 1 ISSN: 1534-3138 ISO Abbreviation: Curr Treat Options Neurol Publication Date: 1999 Jul |
Date Detail:
|
Created Date: 2000-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9815940 Medline TA: Curr Treat Options Neurol Country: - |
Other Details:
|
Languages: ENG Pagination: 263-272 Citation Subset: - |
Affiliation:
|
Departments of Medicine, Neurology, and Clinical Immunology, Australian Neuromuscular Research Institute, 4th Floor, G Block, Queen Elizabeth II Medical Centre, Perth, Australia 6009. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chronic Inflammatory Demyelinating Polyneuropathy.
Next Document: Obstructive Sleep Apnea/Hypopnea Syndrome.