Document Detail

Inflammatory Myofibroblastic Tumor of the Pancreatic Head: An Unusual Cause of Recurrent Acute Pancreatitis - Case Presentation of a Palliative Approach after Failed Resection and Review of the Literature.
MedLine Citation:
PMID:  21113286     Owner:  NLM     Status:  Publisher    
Inflammatory myofibroblastic tumors (IMTs) are a rare cause of echo-poor pancreatic head enlargement. Histologically, IMTs are characterized by spindle-shaped myofibroblasts or fibroblasts accompanied by a mixed immune cell infiltration. The most common localizations of IMTs have been reported in lung, mesentery and omentum, especially in children and young adults. IMTs show infiltrating growth, multilocular appearance and also metastasis have been reported. Curative resection is the only therapeutic option so far. In the palliative situation, evident data and clear guidelines for this rare tumor entity are missing. We report on a 44-year-old male with an unresectable IMT of the pancreatic head causing recurrent episodes of acute pancreatitis that resulted in a chronic obstructive course of the disease. The patient entered a palliative therapeutic regimen including radiation therapy and antiinflammatory medication. In a regular follow-up of 12 months, he presented with stable disease after initial progression. This case of local progressive IMT of the pancreatic head was managed with a palliative therapeutic regimen and is discussed based on the current literature.
Kerstin Schütte; Arne Kandulski; Doerthe Kuester; Frank Meyer; Gero Wieners; Hans-Ulrich Schulz; Peter Malfertheiner
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-10-18
Journal Detail:
Title:  Case reports in gastroenterology     Volume:  4     ISSN:  1662-0631     ISO Abbreviation:  -     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474819     Medline TA:  Case Rep Gastroenterol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  443-451     Citation Subset:  -    
Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany.
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