| Inflammation in overuse tendon injuries. | |
| | |
MedLine Citation:
|
PMID: 21822104 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Overuse tendon injuries present with pain and swelling of the affected tendon with associated decrease in exercise tolerance and function of the limb. After early inflammatory and degenerative hypotheses, the term "tendinopathy" is now deemed a more appropriate reflection of the mixed histopathological picture seen in operative biopsies from affected patients. The condition presents histopathological evidence of "failed healing response," but its etiology remains unclear. The incidence of tendinopathy is increased in individuals with obesity and decreased insulin sensitivity (as seen in type 1 and type 2 diabetes mellitus). These groups of patients also exhibit an increased risk of developing a state of chronic low-grade, systemic inflammation. This paper considers the theoretical bases to discuss whether these conditions may predispose to the development of tendinopathy and the implication that such a relationship may have on its management. |
| | |
Authors:
|
Lucy Battery; Nicola Maffulli |
Related Documents
:
|
8319914 - Abnormalities of human vitreous structure in diabetes. 15657774 - Pars plana vitrectomy with internal limiting membrane removal for macular hole associat... 9215054 - Altered retrobulbar vascular reactivity in early diabetic retinopathy. 8341494 - Retinal nerve fiber layer defect as an early manifestation of diabetic retinopathy. 18579134 - Plasmodium falciparum: development of a transgenic line for screening antimalarials usi... 3527924 - Hepatic glucagon clearance during insulin induced hypoglycemia. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Sports medicine and arthroscopy review Volume: 19 ISSN: 1538-1951 ISO Abbreviation: Sports Med Arthrosc Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-08-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9315689 Medline TA: Sports Med Arthrosc Country: United States |
Other Details:
|
Languages: eng Pagination: 213-7 Citation Subset: IM |
Affiliation:
|
Centre for Sports and Exercise Medicine, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Mile End Hospital, London, England. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of metalloproteinases in rotator cuff tear.
Next Document: Role of growth factors in rotator cuff healing.