Document Detail


Inflammation and cardiovascular disease mechanisms.
MedLine Citation:
PMID:  16470012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The traditional view of atherosclerosis as a lipid storage disease crumbles in the face of extensive and growing evidence that inflammation participates centrally in all stages of this disease, from the initial lesion to the end-stage thrombotic complications. Investigators now appreciate that narrowing arteries do not necessarily presage myocardial infarction and that simply treating narrowed blood vessels does not prolong life. Although invasive approaches such as angioplasty and coronary artery bypass will remain necessary in some cases, we now understand that at least some of the cardiovascular benefits attributable to medical treatment and lifestyle modification (diet and physical activity) may result from reductions in inflammatory processes.
Authors:
Peter Libby
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  83     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-10     Completed Date:  2006-03-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  456S-460S     Citation Subset:  AIM; IM    
Affiliation:
Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. plibby@rics.bwh.harvard.edu
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MeSH Terms
Descriptor/Qualifier:
Aging / physiology*
Atherosclerosis / etiology,  prevention & control
Cardiovascular Diseases / etiology,  prevention & control*,  therapy
Diet*
Exercise / physiology*
Humans
Inflammation / complications*,  therapy
Life Style

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