Document Detail

Inflammation and cancer revisited: an hypothesis on the oncogenic potential of the apoptotic tumor cell.
MedLine Citation:
PMID:  23320865     Owner:  NLM     Status:  MEDLINE    
It is well known that an important property of apoptosis is the prevention of cancer. However, it is becoming increasingly clear that apoptotic cells have the capacity to activate reparative and regenerative responses, which have the potential to make significant impact on pathological processes underlying autoimmune disease and cancer. Those properties of apoptotic cells that influence their immediate microenvironment are reviewed here in the context of cancer progression and treatment.
Christopher D Gregory
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-02-14
Journal Detail:
Title:  Autoimmunity     Volume:  46     ISSN:  1607-842X     ISO Abbreviation:  Autoimmunity     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-12     Completed Date:  2013-12-09     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  8900070     Medline TA:  Autoimmunity     Country:  England    
Other Details:
Languages:  eng     Pagination:  312-6     Citation Subset:  IM    
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MeSH Terms
Apoptosis / genetics,  immunology*
Autoimmune Diseases / immunology,  pathology,  therapy
Cell Transformation, Neoplastic / immunology,  pathology
Disease Progression
Inflammation / immunology,  pathology,  therapy
Neoplasms / immunology*,  pathology*,  therapy
Oncogenes / immunology
Grant Support
G0901697//Medical Research Council; //Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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