Document Detail


Inflammation, brain damage and visual dysfunction in preterm infants.
MedLine Citation:
PMID:  16581321     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Antenatal intrauterine infection and the fetal inflammatory response appear to be important pathogenetic factors in preterm birth and subsequent neonatal disorders of the lung and brain. In this paper, we expand this concept to include visual dysfunction. Although present data tend to support our notion, we suggest that more experimental and epidemiological research is needed to elucidate mechanisms of infection/inflammation-induced damage to the eye and visual brain pathways of preterm infants.
Authors:
Olaf Dammann; Alan Leviton
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2006-03-31
Journal Detail:
Title:  Seminars in fetal & neonatal medicine     Volume:  11     ISSN:  1744-165X     ISO Abbreviation:  -     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-07-18     Completed Date:  2007-02-27     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  101240003     Medline TA:  Semin Fetal Neonatal Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  363-8     Citation Subset:  IM    
Affiliation:
Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany. dammann.olaf@mh-hannover.de
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MeSH Terms
Descriptor/Qualifier:
Brain Injuries / complications,  etiology*
Chorioamnionitis / pathology
Female
Fetal Diseases / pathology
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology*
Inflammation / etiology*
Pregnancy
Premature Birth / etiology
Retinopathy of Prematurity / etiology
Vision Disorders / etiology*
Grant Support
ID/Acronym/Agency:
U01 NS 40069-01A2/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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