Document Detail

Inflaming hypothalamic neurons raises blood pressure.
MedLine Citation:
PMID:  21723497     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Obesity and hypertension are strongly associated, and neural dysfunction has been implicated in both. The hypothalamus integrates signals regulating blood pressure and energy homeostasis. A recent paper in Nature Medicine (Purkayastha et al., 2011) suggests that obesity and hypertension are caused by inflammation in distinct hypothalamic neuronal populations.
Kamal Rahmouni; Robin L Davisson; Curt D Sigmund
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell metabolism     Volume:  14     ISSN:  1932-7420     ISO Abbreviation:  Cell Metab.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-04     Completed Date:  2011-10-27     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  101233170     Medline TA:  Cell Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3-4     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
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MeSH Terms
Grant Support
P01 HL084207/HL/NHLBI NIH HHS; P01 HL084207-04/HL/NHLBI NIH HHS; R01 HL061446/HL/NHLBI NIH HHS; R01 HL061446-13/HL/NHLBI NIH HHS; R01 HL063887/HL/NHLBI NIH HHS; R01 HL063887-10A1/HL/NHLBI NIH HHS; R37 HL048058/HL/NHLBI NIH HHS; R37 HL048058-19/HL/NHLBI NIH HHS
Comment On:
Nat Med. 2011 Jul;17(7):883-7   [PMID:  21642978 ]

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