Document Detail

Infective endocarditis in infants and children during the past ten years.
MedLine Citation:
PMID:  8167986     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Infective endocarditis occurs infrequently in the general pediatric population, but is often associated in patients with underlying heart disease. Even today it remains a serious threat leading to relevant mortality in all pediatric groups, in spite of better antibiotic treatment and prophylactic measures for endangered persons. This retrospective analysis reports experience here with infective endocarditis in children. METHODS: The clinical and laboratory findings in 28 children with 30 episodes of infective endocarditis, from July 1984 to June 1993, were reviewed retrospectively. RESULTS: Twenty-one children (75 percent) had congenital heart disease, three (11 percent) had rheumatic heart disease and four (14 percent) had no underlying cardiac abnormality prior to presentation. Twenty-six (87 percent) of the 30 episodes had positive blood cultures. The most common organism isolated was streptococcus viridans (14 percent), followed by staphylococcus aureus (7 percent). Echocardiography identified vegetation in 21 of 28 (75 percent) patients. Twenty children were successfully treated medically. Four developed complications requiring surgery, of whom two died. A total of six children (21 percent) died of the disease or its complications. There were a high case fatality rate for children below the age of two years (75 percent), and children without an underlying cardiac abnormality (50 percent). CONCLUSIONS: It was concluded that patient survival is dependent on several factors which include early diagnosis, appropriate antimicrobial therapy and aggressive surgical intervention.
S C Chen; K S Hsieh; Y J Wang; Y J Chen; C S Chi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed     Volume:  53     ISSN:  0578-1337     ISO Abbreviation:  Zhonghua Yi Xue Za Zhi (Taipei)     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-05-27     Completed Date:  1994-05-27     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0005327     Medline TA:  Zhonghua Yi Xue Za Zhi (Taipei)     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  109-15     Citation Subset:  IM    
Department of Pediatrics, Taichung Veterans General Hospital, Taiwan, R.O.C.
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MeSH Terms
Child, Preschool
Endocarditis, Bacterial / etiology*,  therapy
Heart Defects, Congenital / complications
Infant, Newborn
Retrospective Studies
Rheumatic Heart Disease / complications
Staphylococcal Infections*
Streptococcal Infections*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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