Document Detail


Infectious mononucleosis and related syndromes.
MedLine Citation:
PMID:  217270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The "mono syndrome" is an acute febrile disease of older children and young adults which involves the lymphatic system and is characterized hematologically by the presence of 50% or more lymphocytes and monocytes and 10% or more atypical lymphocytes. Epstein-Barr virus (EBV) causes over 90% of the syndrome, cytomegalovirus (CMV) about 5% to 7%, and Toxoplasma gondii less than 1%. Viral hepatitis, adenovirus, rubella, and herpes simplex are rare causes. Only EBV produces classical heterophile-positive infectious mononucleosis. This article reviews the epidemiological and clinical features of this syndrome.
Authors:
A S Evans
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  276     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:    1978 Nov-Dec
Date Detail:
Created Date:  1979-04-28     Completed Date:  1979-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  325-39     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Antibodies / analysis
Antibodies, Viral / analysis
Blood Transfusion / adverse effects
Child
Child, Preschool
Cricetinae
Cytomegalovirus / immunology
Diagnosis, Differential
Female
Herpesvirus 4, Human / immunology
Humans
Infant
Infant, Newborn
Infectious Mononucleosis / diagnosis*,  epidemiology,  etiology
Leukocyte Count
Male
Monocytes
Pregnancy
Syndrome
Toxoplasma / immunology
Chemical
Reg. No./Substance:
0/Antibodies; 0/Antibodies, Viral

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