Document Detail


Infectious crystalline keratopathy and endophthalmitis secondary to Mycobacterium abscessus in a monocular patient with Stevens-Johnson syndrome.
MedLine Citation:
PMID:  10030567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe the clinical and laboratory features of infectious crystalline keratopathy and endophthalmitis secondary to Mycobacterium abscessus in a patient with Stevens-Johnson syndrome. METHOD: Case report. A 19-year-old man with a history of Stevens-Johnson syndrome and multiple corneal transplants developed white crystalline corneal infiltrates. RESULTS: Anterior chamber aspirate disclosed acid-fast bacilli. A repeat corneal transplant was performed and antibiotic therapy begun. Histopathology showed focal acute inflammation surrounding collections of acid-fast bacilli, which were speciated as M. abscessus. CONCLUSIONS: M. abscessus is a cause of infectious crystalline keratopathy and endophthalmitis. Risk factors include ocular surface disease, corneal transplantation, and immunosuppressive therapy.
Authors:
H S Uy; Q D Nguyen; M L Durand; B Paton; C S Foster
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  127     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-02-26     Completed Date:  1999-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  209-10     Citation Subset:  AIM; IM    
Affiliation:
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amikacin / therapeutic use
Anterior Chamber / microbiology
Azithromycin / therapeutic use
Corneal Diseases / diagnosis,  drug therapy,  microbiology*
Drug Therapy, Combination / therapeutic use
Endophthalmitis / diagnosis,  drug therapy,  microbiology*
Eye Infections, Bacterial / diagnosis,  drug therapy,  microbiology*
Humans
Keratoplasty, Penetrating
Male
Mycobacterium / isolation & purification
Mycobacterium Infections / diagnosis,  drug therapy,  microbiology*
Stevens-Johnson Syndrome / complications*
Vision, Monocular*
Chemical
Reg. No./Substance:
37517-28-5/Amikacin; 83905-01-5/Azithromycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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