| Infectious crystalline keratopathy caused by Streptococcus Abiotrophia defectiva. | |
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MedLine Citation:
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PMID: 20508513 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report the first case of Streptococcus Abiotrophia defectiva-associated crystalline keratopathy. METHODS: An 83-year-old woman underwent penetrating keratoplasty for pseudophakic bullous keratopathy in the OD. Ten months after surgery, the patient presented with decreased visual acuity in the OD. Slit-lamp examination showed crystalline keratopathy. Corneal scrapings were negative, and the patient was treated empirically with 2 fortified antibiotics (ciprofloxacin and vancomycin). Despite these treatments, the surface of the infiltrate increased and corneal regrafting was performed 6 weeks later. The excised prior graft was evaluated microbiologically [culture and polymerase chain reaction (PCR)] and histopathologically. RESULTS: In the explanted corneal graft, cultures grew Streptococcus A. defectiva, and its DNA was demonstrated by broad-range PCR (16S ribosomal DNA). CONCLUSIONS: A. defectiva can be a causative organism of infectious crystalline keratopathy. Risk factors may include long-term corticosteroid use and prior corneal transplantation. The present case confirms that PCR can be a useful technique in the diagnosis of deep infectious keratitis. |
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Authors:
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Florence Abry; Arnaud Sauer; Philippe Riegel; Maher Saleh; David Gaucher; Claude Speeg-Schatz; Tristan Bourcier |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cornea Volume: 29 ISSN: 1536-4798 ISO Abbreviation: Cornea Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-27 Completed Date: 2010-10-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8216186 Medline TA: Cornea Country: United States |
Other Details:
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Languages: eng Pagination: 934-6 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University Hospital of Strasbourg, Strasbourg, France. florence.abry@chru-strasbourg.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Anti-Bacterial Agents / therapeutic use Bacterial Typing Techniques Corneal Ulcer / diagnosis, microbiology*, surgery DNA, Bacterial / analysis Drug Therapy, Combination Eye Infections, Bacterial / diagnosis, microbiology*, surgery Female Humans Keratoplasty, Penetrating Microbial Sensitivity Tests Polymerase Chain Reaction RNA, Ribosomal, 16S / genetics Reoperation Streptococcal Infections / diagnosis, microbiology*, surgery Streptococcus / genetics, isolation & purification* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/DNA, Bacterial; 0/RNA, Ribosomal, 16S |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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