Document Detail

Infections with Rhodococcus equi in children.
MedLine Citation:
PMID:  1889184     Owner:  NLM     Status:  MEDLINE    
Three cases of serious infection in children, including the first two reports of bacteremia, due to Rhodococcus equi are described. Only seven pediatric cases have been reported to date. In the laboratory, R. equi can easily be misidentified as a nonpathogenic Corynebacterium spp. (diphtheroid) or a Mycobacterium spp. Despite an overall mortality rate of 25% in adults, no pediatric deaths have occurred due to R. equi. The organism is generally susceptible to vancomycin, aminoglycosides, chloramphenicol, and erythromycin, but, optimal duration of antibiotic therapy is unknown. Treatment with multiple antibiotics was successful in all three cases reported here. Although only a small number of cases have been reported in children, R. equi appears to be an important pediatric pathogen.
K L McGowan; M F Mangano
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Diagnostic microbiology and infectious disease     Volume:  14     ISSN:  0732-8893     ISO Abbreviation:  Diagn. Microbiol. Infect. Dis.     Publication Date:    1991 Jul-Aug
Date Detail:
Created Date:  1991-10-17     Completed Date:  1991-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8305899     Medline TA:  Diagn Microbiol Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-52     Citation Subset:  IM    
Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia.
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MeSH Terms
Actinomycetales Infections / drug therapy,  microbiology*
Anti-Bacterial Agents
Child, Preschool
Drug Therapy, Combination / therapeutic use
Rhodococcus / isolation & purification*
Sepsis / drug therapy,  microbiology*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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