Document Detail


Infections of the central nervous system.
MedLine Citation:
PMID:  1456278     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Infections of the central nervous system are common, serious medical conditions. One hundred consecutive adult cases with purulent meningitis of known etiology encountered by the Medical Service at Parkland Memorial Hospital were reviewed. Streptococcus pneumoniae was the most common pathogen (56 cases), followed by Neisseria meningitidis (16 cases) and Listeria monocytogenes (seven cases). Hemophilus influenzae, Staphylococcus aureus, and streptococci each accounted for five cases. An additional 15 patients had purulent meningitis with a pathogen being isolated. Twenty five purulent meningitis cases of known etiology after trauma or neurosurgery were reviewed. Staphylococcus aureus (five cases), Staphylococcus epidermidis (four cases), and gram negative bacilli (14 cases) were the most common pathogens. Review of intracranial suppurative infections demonstrated advances in microbiology, antibiotic therapy, and imaging, leading to improvements in therapy. Subdural empyema continues to be a difficult diagnosis to make and apparently is related to the anatomic pathology of the infectious process. To illustrate salient features about granulomatous meningitis and encephalitis, cases of tuberculous meningitis, herpes simplex encephalitis, St. Louis encephalitis, and encephalitis of undetermined etiology are presented and discussed.
Authors:
J P Luby
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  304     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-06     Completed Date:  1993-01-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  379-91     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Brain Abscess / drug therapy,  microbiology,  physiopathology
Brain Diseases / diagnosis,  drug therapy,  microbiology*,  physiopathology
Encephalitis / diagnosis,  drug therapy,  microbiology,  physiopathology
Female
Herpes Simplex / complications
Humans
Male
Meningitis, Bacterial / diagnosis,  drug therapy,  microbiology,  physiopathology
Middle Aged
Pregnancy
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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