| Infection with fasciola hepatica - a case series | |
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MedLine Citation:
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PMID: 20183778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: Described are the clinical and, especially, the contrast-enhanced ultrasonographic presentation and recovery of four cases of fascioliasis occurring between December 2008 and February 2009. MATERIALS AND METHODS: A detailed history, clinical examination and laboratory investigation were followed by contrast-enhanced ultrasonography of the liver and serological evidence for the presence of antibodies. A final contrast-enhanced ultrasound was performed 6 weeks after treatment with triclabendazole. RESULTS: The patients displayed a variety of symptoms ranging from vasospastic myocardial infarction diagnosed via coronary angiography and a first-time occurrence of migraine as a result of hypereosinophilia to fever with weight loss and tumor-like liver lesions. The contrast-enhanced ultrasonographic hepatic changes in fascioliasis are characterized by segmental arterial hyperemia with emphasis on the liver periphery and subcapsular canalicular sparing corresponding to parenchymal necrosis and hemorrhage. In the later phases areas with inflammatory changes were unmasked due to phlebitis of the small portal vessels and granulomatous parenchymal changes. All four patients were successfully treated with triclabendazole without experiencing any serious side effects. CONCLUSION: Contrast-enhanced ultrasonography is well suited for the diagnosis and monitoring of hepatic fascioliasis. |
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Authors:
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D Weiss; G Marti; W Mouton; W Wermke; O Kummer |
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Publication Detail:
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Type: Case Reports; English Abstract; Journal Article Date: 2010-02-24 |
Journal Detail:
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Title: Ultraschall in der Medizin (Stuttgart, Germany : 1980) Volume: 31 ISSN: 1438-8782 ISO Abbreviation: Ultraschall Med Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-22 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303585 Medline TA: Ultraschall Med Country: Germany |
Other Details:
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Languages: ger Pagination: 175-81 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart . New York. |
Affiliation:
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Medizinische Klinik, Spital STSAG, Thun, Schweiz. daniel.weiss@spitalstsag.ch |
Vernacular Title:
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Fasciola-hepatica-Infektionen in der Schweiz - eine Fallserie. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anthelmintics / therapeutic use Benzimidazoles / therapeutic use Biopsy Contrast Media / administration & dosage Diagnosis, Differential Fascioliasis / drug therapy, pathology, ultrasonography* Female Follow-Up Studies Humans Liver / pathology, ultrasonography Male Middle Aged Phospholipids / diagnostic use Sensitivity and Specificity Sulfur Hexafluoride / diagnostic use Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Anthelmintics; 0/Benzimidazoles; 0/Contrast Media; 0/Phospholipids; 0/contrast agent BR1; 2551-62-4/Sulfur Hexafluoride; 68786-66-3/triclabendazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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