Document Detail

Infection with Chlamydia pneumoniae in infants and children with acute lower respiratory tract disease.
MedLine Citation:
PMID:  7746693     Owner:  NLM     Status:  MEDLINE    
The role of Chlamydia pneumoniae in the etiology of acute lower respiratory tract infections in infants and children is little understood. We studied the prevalence of C. pneumoniae infection in hospitalized infants and children with acute lower respiratory tract disease by cell culture, polymerase chain reaction (PCR), enzyme immunoassay and serology. Of 290 patients with a mean age of 3.7 years, only 3 (1%) were identified to be infected with C. pneumoniae. One child was positive in the cell culture as well as the PCR assay. Another infant was PCR-positive only and serologic evidence of infection was observed in a culture- and PCR-negative child. Chlamydia trachomatis was not detected in any patient specimen by either culture or PCR. Results of this study indicate that C. pneumoniae plays a minor role in the etiology of respiratory tract infections in infants and young children.
C A Jantos; B Wienpahl; H G Schiefer; F Wagner; J H Hegemann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  14     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-06-12     Completed Date:  1995-06-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  117-22     Citation Subset:  IM    
Institut für Medizinische Mikrobiologie, Giessen, Germany.
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MeSH Terms
Acute Disease
Age Distribution
Child, Preschool
Chlamydia Infections / diagnosis,  epidemiology*,  etiology
Chlamydophila pneumoniae* / isolation & purification
Immunoenzyme Techniques
Infant, Newborn
Polymerase Chain Reaction
Respiratory Tract Infections / diagnosis,  epidemiology,  microbiology*
Serologic Tests

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