| Infection resistance of unreamed solid, hollow slotted and cannulated intramedullary nails: an in-vivo experimental comparison. | |
| | |
MedLine Citation:
|
PMID: 16022994 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Infection continues to be a problematic complication of fracture treatment, particularly in severe open fractures. The implant design and material as well as implantation technique play an important role in the pathogenesis of local infection. The aim of our study was to determine if the local resistance to infection of a cannulated IM nail is less than that of a solid nail and more similar to that of a hollow nail. In 65 female White Zealand rabbits, the intramedullary cavity was inoculated with matching concentrations of Staphylococcus aureus, and one of the three nails was inserted. The solid nail had a greater than twofold higher resistance to infection (23%) compared to that of the other two nails (hollow, 65%; cannulated, 61%) which was statistically significant (p<0.02). No difference in infection resistance was detected between the hollow slotted and cannulated nail designs (p=1). Although these experimental results may be clinically considered, direct extrapolation to clinical infection rates is ill advised. |
| | |
Authors:
|
J Horn; U Schlegel; C Krettek; K Ito |
Related Documents
:
|
9923944 - Impact of infection on mortality and hospitalization in the north east of england. 9547064 - Effect of peganum harmala extract on root tips of allium cepa. 16354474 - Incidence of fungi pathogens associated with root canal treatments, in benin city, nige... 18943544 - Recovery in apple trees infected with the apple proliferation phytoplasma: an ultrastru... 20086944 - Pitted keratolysis: a common infection of active feet. 23225874 - Parasite-augmented mate choice and reduction in innate fear in rats infected by toxopla... |
Publication Detail:
|
Type: Journal Article Date: 2005-01-18 |
Journal Detail:
|
Title: Journal of orthopaedic research : official publication of the Orthopaedic Research Society Volume: 23 ISSN: 0736-0266 ISO Abbreviation: J. Orthop. Res. Publication Date: 2005 Jul |
Date Detail:
|
Created Date: 2005-07-18 Completed Date: 2005-08-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8404726 Medline TA: J Orthop Res Country: United States |
Other Details:
|
Languages: eng Pagination: 810-5 Citation Subset: IM |
Affiliation:
|
AO Research Institute, Clavadelerstrasse, 7270 Davos Platz, Davos, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bone Nails* Female Fracture Fixation, Internal* Osteomyelitis / microbiology, prevention & control*, radiography Postoperative Complications / microbiology, prevention & control Prosthesis Design Rabbits Staphylococcal Infections / prevention & control*, radiography Tibial Fractures / radiography, surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Biomechanical and allergological characteristics of a biodegradable poly(D,L-lactic acid) coating fo...
Next Document: Characterization of a chronic infection in an internally-stabilized segmental defect in the rat femu...