Document Detail


Infection and preterm labor.
MedLine Citation:
PMID:  11100293     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are many conditions, such as non-white race, young maternal age, and uterine malformations, that have been associated with preterm birth that are not amenable to intervention. Maternal cervical and intrauterine infection and inflammation may have a primary causative role in a fraction of the cases of preterm birth and preterm rupture of membranes and may also interact adversely with a variety of maternal (shortened cervix, smoking) and fetal factors (polyhydramnios, multifetal gestation) to decrease the threshold to preterm birth. Further studies are needed to better-define the link between various maternal microbial colonizations and preterm delivery, with the possibility to establish new screening and treatment recommendations. Because of the innumerable causes of preterm birth, a new strategy of targeted treatment of cervical or vaginal infections may lead to only a modest reduction in the incidence of this devastating problem of modern obstetrics.
Authors:
N P Yost; S M Cox
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  43     ISSN:  0009-9201     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-21     Completed Date:  2001-05-10     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  759-67     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75390-9032, USA.
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MeSH Terms
Descriptor/Qualifier:
Chronic Disease
Female
Humans
Obstetric Labor, Premature / microbiology*
Pregnancy
Pregnancy Complications, Infectious*
Urinary Tract Infections / complications
Vaginosis, Bacterial / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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