Document Detail

Infection and disease after perinatal exposure to Chlamydia trachomatis in Nairobi, Kenya.
MedLine Citation:
PMID:  3411148     Owner:  NLM     Status:  MEDLINE    
A cohort of 49 infants exposed to maternal chlamydial infection and 40 nonexposed infants was studied after birth for a mean of 3.3 +/- 1.5 and 3 +/- 1.7 mo, respectively. Eighteen (37%) exposed infants had at least one positive culture for Chlamydia trachomatis, whereas C. trachomatis was not isolated from any of the nonexposed infants. Eighteen (37%) exposed infants developed ophthalmia neonatorum (n = 12) or infant conjunctivitis (n = 7), compared with six (15%) of the nonexposed infants (P = .04). Six (12%) exposed infants developed pneumonia, compared with none of the 40 nonexposed infants (P = .05). One infant in the exposed group died during follow-up. These results suggest that appreciable infant morbidity in Kenya may be associated with the high prevalence of maternal chlamydial infection.
P Datta; M Laga; F A Plummer; J O Ndinya-Achola; P Piot; G Maitha; A R Ronald; R C Brunham
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  158     ISSN:  0022-1899     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-10-04     Completed Date:  1988-10-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  524-8     Citation Subset:  AIM; IM    
Department of Medical Microbiology, University of Nairobi, Republic of Kenya.
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MeSH Terms
Chlamydia Infections / epidemiology*,  transmission
Chlamydia trachomatis
Cough / epidemiology
Follow-Up Studies
Gastroenteritis / epidemiology
Infant, Newborn
Ophthalmia Neonatorum / epidemiology
Pneumonia / epidemiology
Prospective Studies

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