Document Detail

Infection-associated vascular lesions in acquired immunodeficiency syndrome patients.
MedLine Citation:
PMID:  2551814     Owner:  NLM     Status:  MEDLINE    
Several reports have recently appeared in the literature describing "unique" non-neoplastic vascular lesions in patients with the acquired immunodeficiency syndrome (AIDS). These lesions may be mistaken clinically and histologically for Kaposi's sarcoma. The terms epithelioid angiomatosis, epithelioid or histiocytoid hemangioma, and pyogenic granuloma have all been used to describe a similar entity in which cat scratch disease bacillus (CSDB) was subsequently identified. Lesions closely resembling this entity occur in patients with bartonellosis. We report a case of a cutaneous vascular lesion on the hand of an AIDS patient in which cytomegalovirus (CMV) and organisms consistent with CSDB were both found. Simultaneous infections with CMV and CSDB have not been previously described. The presence of these organisms in and around endothelial cells may provide the common stimulus for the formation of these reactive vascular proliferations.
J Abrams; A I Farhood
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  20     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-14     Completed Date:  1989-11-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1025-6     Citation Subset:  IM; X    
Department of Pathology, Pennsylvania Hospital, Philadelphia.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications*,  pathology
Angiomatosis / complications
Cat-Scratch Disease / complications*,  diagnosis,  pathology
Cytomegalovirus / isolation & purification,  ultrastructure
Cytomegalovirus Infections / complications*,  diagnosis,  pathology
Diagnosis, Differential
Endothelium, Vascular / microbiology,  pathology,  ultrastructure
HIV Seropositivity / complications
HIV-1 / isolation & purification,  ultrastructure
Microscopy, Electron
Sarcoma, Kaposi / diagnosis,  pathology
Skin Neoplasms / complications

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