Document Detail

Infection as a predominant cause of perinatal mortality.
MedLine Citation:
PMID:  6281706     Owner:  NLM     Status:  MEDLINE    
During a 15-month period, all 34 infants delivered at the department of obstetrics and gynecology at University Hospital in Lund, Sweden, who died perinatally or neonatally were included in a prospective study of causes of death. Autopsies--including extensive culturing of specimens for bacteria, chlamydia, fungi, mycoplasmas, and viruses--were performed for all infants. Maternal sera obtained during pregnancy and after delivery were examined regarding titers against a number of microorganisms. During the study period, the perinatal mortality rate was 0.60% and the neonatal mortality rate 0.56%. It was found that 37% of the deaths were caused by lethal malformations, 17% by idiopathic respiratory distress syndrome, and 9% by ablatio placentae. However, no less than 21% occurred as a direct consequence of infections, including 2 deaths caused by group B streptococci, 2 by Coxsackie B virus, and 3 deaths each by Hemophilus influenzae, Pseudomonas pyocyanea, and Candida albicans. A 6-month study of late abortions revealed another case of intrauterine group B streptococcal infection. The study has demonstrated that autopsy, including microbial examination, is recommended in all cases of perinatal and neonatal deaths.
K K Christensen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  59     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-07-19     Completed Date:  1982-07-19     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  499-508     Citation Subset:  AIM; IM    
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MeSH Terms
Abortion, Septic
Congenital Abnormalities / mortality
Coxsackievirus Infections / mortality
Enterovirus B, Human
Fetal Death / etiology*
Infant, Newborn
Infant, Newborn, Diseases / mortality*
Infection / mortality*
Placenta / microbiology
Pregnancy Complications, Infectious*
Prospective Studies
Respiratory Distress Syndrome, Newborn / mortality
Streptococcal Infections / mortality
Streptococcus agalactiae

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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