| InfarctSizer: computing infarct volume from brain images of a stroke animal model. | |
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MedLine Citation:
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PMID: 20799117 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Many computational methods for determining the infarct volume from the image of 2,3,5-triphenyltetrazolium chloride-stained brain slices rely on the discretion of the user to determine the infarct region by visual inspection. Once the user determines the infarct boundary by visual inspection, the methods compute the area within the boundary with the assumption that all the spots within the boundary have been infarcted at the same level. However, in the same brain image, partially infarcted spots often tend to appear pinkish whereas fully or severely infarcted spots appear white. We developed a program called InfarctSizer, which automatically detects the infarct region and computes the infarct volume proportional to infarction levels. Comparison of InfarctSizer with other methods shows that InfarctSizer computes the infarct volume more accurately and efficiently than other methods. InfarctSizer and sample brain images are available at http://wilab.inha.ac.kr/brainimage. |
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Authors:
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Jaetak Lee; Ja-Kyeong Lee; Kyungsook Han |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Computer methods in biomechanics and biomedical engineering Volume: 14 ISSN: 1476-8259 ISO Abbreviation: Comput Methods Biomech Biomed Engin Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9802899 Medline TA: Comput Methods Biomech Biomed Engin Country: England |
Other Details:
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Languages: eng Pagination: 497-504 Citation Subset: IM |
Affiliation:
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School of Computer Science and Engineering, Inha University, Incheon, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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