| Infantile hemangioendothelioma with a highly elevated serum alpha-fetoprotein level. | |
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MedLine Citation:
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PMID: 9638427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infantile hemangioendothelioma is the most common vascular tumor in infancy. A three-month-old infant was admitted to the hospital for hepatomegaly. Abdominal ultrasonography, a CT-scan, and MRI studies demonstrated bilateral diffuse hepatic nodules, which were characteristic of hepatic hemangioendothelioma. A highly elevated alpha-fetoprotein (AFP) level misled us to an impression of hepatoblastoma, but the pathology report through an open biopsy disclosed a liver hemangioendothelioma. The patient responded to methylprednisolone therapy. A follow-up sonogram revealed regression of the hepatic masses. This case emphasizes that an elevated AFP level of up to 400 ng/ml is normally found in some neonates until two months of age. Careful interpretation of this value is very important, especially when it is associated with a hepatic tumor. Herein, we present a case of infantile hemangioendothelioma in a three-month-old boy with a highly elevated serum AFP. |
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Authors:
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S J Han; C C Tsai; H M Tsai; Y J Chen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 45 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 1998 Mar-Apr |
Date Detail:
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Created Date: 1998-09-03 Completed Date: 1998-09-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: GREECE |
Other Details:
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Languages: eng Pagination: 459-61 Citation Subset: IM |
Affiliation:
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Department of Radiology, Tainan Municipal Hospital, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diagnostic Imaging Glucocorticoids / therapeutic use Hemangioendothelioma / blood, diagnosis*, drug therapy Humans Infant Liver Neoplasms / blood, diagnosis*, drug therapy Male Methylprednisolone / therapeutic use Tumor Markers, Biological / blood* alpha-Fetoproteins / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 0/Tumor Markers, Biological; 0/alpha-Fetoproteins; 83-43-2/Methylprednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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