Document Detail


Infantile hemangioendothelioma with a highly elevated serum alpha-fetoprotein level.
MedLine Citation:
PMID:  9638427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Infantile hemangioendothelioma is the most common vascular tumor in infancy. A three-month-old infant was admitted to the hospital for hepatomegaly. Abdominal ultrasonography, a CT-scan, and MRI studies demonstrated bilateral diffuse hepatic nodules, which were characteristic of hepatic hemangioendothelioma. A highly elevated alpha-fetoprotein (AFP) level misled us to an impression of hepatoblastoma, but the pathology report through an open biopsy disclosed a liver hemangioendothelioma. The patient responded to methylprednisolone therapy. A follow-up sonogram revealed regression of the hepatic masses. This case emphasizes that an elevated AFP level of up to 400 ng/ml is normally found in some neonates until two months of age. Careful interpretation of this value is very important, especially when it is associated with a hepatic tumor. Herein, we present a case of infantile hemangioendothelioma in a three-month-old boy with a highly elevated serum AFP.
Authors:
S J Han; C C Tsai; H M Tsai; Y J Chen
Related Documents :
23803677 - Hemophagocytic lymphohistiocytosis in a newborn infant born to a mother with sjögren s...
9880637 - Evaluation of mebrofenin hepatoscintigraphy in neonatal-onset jaundice.
12677267 - Transient cholestasis in newborn infants with perinatal asphyxia.
11735147 - Congenital atresia of the orifice of the submandibular duct: a report of 2 cases and re...
10485307 - Platelet-activating factor concentrations in healthy and septic neonates.
10214817 - Perinatal transmission of human papillomavirus from gravidas with latent infections.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  45     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    1998 Mar-Apr
Date Detail:
Created Date:  1998-09-03     Completed Date:  1998-09-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  GREECE    
Other Details:
Languages:  eng     Pagination:  459-61     Citation Subset:  IM    
Affiliation:
Department of Radiology, Tainan Municipal Hospital, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Diagnostic Imaging
Glucocorticoids / therapeutic use
Hemangioendothelioma / blood,  diagnosis*,  drug therapy
Humans
Infant
Liver Neoplasms / blood,  diagnosis*,  drug therapy
Male
Methylprednisolone / therapeutic use
Tumor Markers, Biological / blood*
alpha-Fetoproteins / analysis*
Chemical
Reg. No./Substance:
0/Glucocorticoids; 0/Tumor Markers, Biological; 0/alpha-Fetoproteins; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mesenteric neurofibroma with von Recklinghausen's disease: a case report.
Next Document:  Carcinoembryonic antigen and intra-arterial chemotherapy response of liver metastases.