Document Detail

Infantile disseminated visceral giant cell arteritis presenting as sudden infant death.
MedLine Citation:
PMID:  10338078     Owner:  NLM     Status:  MEDLINE    
The rare clinicopathological entity 'disseminated visceral giant cell arteritis' (DVGCA) was first described in 1978. It is characterized by widespread small-vessel giant cell angitis and extravascular granulomas. A normal and healthy 7-month-old boy who presented unexpectedly with sudden infant death syndrome (SIDS) is reported. Histological examination at autopsy revealed giant cell angitis of the aorta, common carotid, coronary, pulmonary, celiac, mesenteric and common iliac arteries. There were also granulomas in the tracheal wall and liver. To our knowledge, this is the first documented case of DVGCA occurring in an infant younger than 12 months of age. A review of the literature on DVGCA is presented in this report, and the differential diagnosis is discussed.
Y Kagata; O Matsubara; S Ogata; J T Lie; E J Mark
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pathology international     Volume:  49     ISSN:  1320-5463     ISO Abbreviation:  Pathol. Int.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-07-13     Completed Date:  1999-07-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9431380     Medline TA:  Pathol Int     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
Department of Pathology, National Defense Medical College, Tokorozawa, Saitama, Japan.
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MeSH Terms
Arteries / pathology
Coronary Vessels / pathology
Diagnosis, Differential
Fatal Outcome
Giant Cell Arteritis / pathology*
Granuloma / pathology
Hepatic Veins / pathology
Lung / pathology
Sudden Infant Death / pathology*
Vasculitis / pathology*

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