Document Detail

Infantile botulism: pitfalls in electrodiagnosis.
MedLine Citation:
PMID:  10190265     Owner:  NLM     Status:  MEDLINE    
Botulism in infants, unless recognized early, is associated with high mortality and morbidity. The diagnosis is suspected when infants present with sudden onset of weakness, respiratory failure, and constipation and is confirmed by demonstration of botulinum toxin in stool several weeks later. Electrodiagnosis allows quick and reliable confirmation of botulism. Low-amplitude compound muscle action potentials, tetanic or post-tetanic facilitation, and the absence of post-tetanic exhaustion support the diagnosis. Two infants with confirmed botulism did not exhibit the characteristic electrodiagnostic features, demonstrating the pitfalls in electrodiagnosis of infantile botulism.
R D Sheth; B P Lotz; K E Hecox; A J Waclawik
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  14     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-05-25     Completed Date:  1999-05-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  156-8     Citation Subset:  IM    
Department of Neurology, University of Wisconsin, Madison 53792-5132, USA.
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MeSH Terms
Botulism / diagnosis*
Clostridium botulinum / isolation & purification
Diagnostic Errors*
Electrodiagnosis / methods*
Feces / microbiology
Muscles / pathology
Comment In:
J Child Neurol. 2000 Sep;15(9):630   [PMID:  11019796 ]

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