| Infantile botulism: pitfalls in electrodiagnosis. | |
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MedLine Citation:
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PMID: 10190265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Botulism in infants, unless recognized early, is associated with high mortality and morbidity. The diagnosis is suspected when infants present with sudden onset of weakness, respiratory failure, and constipation and is confirmed by demonstration of botulinum toxin in stool several weeks later. Electrodiagnosis allows quick and reliable confirmation of botulism. Low-amplitude compound muscle action potentials, tetanic or post-tetanic facilitation, and the absence of post-tetanic exhaustion support the diagnosis. Two infants with confirmed botulism did not exhibit the characteristic electrodiagnostic features, demonstrating the pitfalls in electrodiagnosis of infantile botulism. |
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Authors:
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R D Sheth; B P Lotz; K E Hecox; A J Waclawik |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of child neurology Volume: 14 ISSN: 0883-0738 ISO Abbreviation: J. Child Neurol. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-05-25 Completed Date: 1999-05-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 156-8 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Wisconsin, Madison 53792-5132, USA. sheth@neurology.wisc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Botulism / diagnosis* Clostridium botulinum / isolation & purification Diagnostic Errors* Electrodiagnosis / methods* Feces / microbiology Female Humans Infant Muscles / pathology |
| Comments/Corrections | |
Comment In:
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J Child Neurol. 2000 Sep;15(9):630
[PMID:
11019796
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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