Document Detail


Infantile bilateral striatal necrosis. Clinicopathological classification.
MedLine Citation:
PMID:  3729745     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two cases of infantile bilateral striatal necrosis (IBSN) were studied retrospectively, and the literature was reviewed. The two children had presented with progressive neurologic signs of involuntary movements or muscle hypertonia from infancy. Initial computed tomography scans showed mild atrophy of the caudate nuclei or basal ganglia, and the neuropathologic examination revealed diffuse neuronal loss with some patchy preservation and marked astrogliosis in the striatum and globus pallidus. The 27 reported cases of IBSN were divided into three groups with characteristic clinical and pathologic features: early, acute onset (four cases); early, gradual onset (16 cases); and late onset (seven cases). Although metabolic changes in the developing corpus striatum may be important in the pathogenesis of IBSN, the origin is uncertain.
Authors:
T Mito; T Tanaka; L E Becker; S Takashima; J Tanaka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  43     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-07-30     Completed Date:  1986-07-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  677-80     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Brain / pathology*
Brain Diseases / classification,  pathology*
Child
Corpus Striatum / pathology
Globus Pallidus / pathology
Humans
Infant
Male
Necrosis
Putamen / pathology
Retrospective Studies
Terminology as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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