Document Detail

Infant size at 8 months of age: relationship to maternal use of alcohol, nicotine, and caffeine during pregnancy.
MedLine Citation:
PMID:  6472964     Owner:  NLM     Status:  MEDLINE    
To examine the relationship of maternal alcohol consumption, caffeine use, and smoking to infant size at 8 months of age, a follow-up cohort of 453 infants was examined at birth and again at their 8-month birthday. Even after adjustment for other relevant variables, maternal alcohol use during early pregnancy (average ounces of absolute alcohol by self-report) was significantly related to infant weight and length at 8 months of age but not as strongly related to head circumference. Maternal smoking and caffeine use during pregnancy were not significantly related to infant size at 8 months, although nicotine use had been highly related to the birth size in this sample. Maternal use of marijuana was significantly and negatively related to infant length at 8 months of age, but not to weight or head circumference. The magnitude of the growth retardation is smaller at 8 months than at birth in this sample of infants whose mothers are primarily white, married, and well-educated, and who report a variety of alcohol use patterns. Significance was tested using multiple regression analyses that adjusted for the effects of nicotine use, caffeine use, birth order, maternal height, and gestational age as well as sex and age of infant at examination.
H M Barr; A P Streissguth; D C Martin; C S Herman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pediatrics     Volume:  74     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-10-03     Completed Date:  1984-10-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  336-41     Citation Subset:  AIM; IM    
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MeSH Terms
Alcohol Drinking*
Body Weight* / drug effects
Caffeine / pharmacology
Head / anatomy & histology
Maternal-Fetal Exchange*
Nicotine / pharmacology
Grant Support
Reg. No./Substance:
54-11-5/Nicotine; 58-08-2/Caffeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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