Document Detail

Infant neurological examination from 3 to 12 months: predictive value of the single items.
MedLine Citation:
PMID:  19568999     Owner:  NLM     Status:  MEDLINE    
The prognostic value of the single items of a standardised neurological examination, the Hammersmith Infant Neurologic Examination (HINE), was explored longitudinally in 658 infants at 3, 6, 9 and 12 months post-term age. ROC curves were built based on the presence/absence of cerebral palsy at 2 years of age. Global HINE scores showed very high prediction (ROC curve areas above 0.9) at all ages. The items with the highest predictive value were always movement quality and quantity. In the first semester, among the most predictive items were those assessing tone, while beyond that time they were reflexes and reactions. Our results show that the high predictive value of the HINE across the first year of life is granted by the successful combination of different groups of items for each age-period. This should be recognised in clinical practice when assessing the significance of individual neurological profiles.
A Pizzardi; D M M Romeo; M Cioni; M G Romeo; A Guzzetta
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Publication Detail:
Type:  Journal Article     Date:  2009-06-30
Journal Detail:
Title:  Neuropediatrics     Volume:  39     ISSN:  1439-1899     ISO Abbreviation:  Neuropediatrics     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-07-01     Completed Date:  2009-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  344-6     Citation Subset:  IM    
Division of Child Neurology and Psychiatry, Department of Paediatrics, University of Catania, Catania, Italy.
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MeSH Terms
Age Factors
Birth Weight
Cerebral Palsy / diagnosis*
Child, Preschool
Follow-Up Studies
Gestational Age
Infant, Newborn
Infant, Premature, Diseases / diagnosis*
Intensive Care Units, Neonatal
Neurologic Examination / statistics & numerical data*
Prospective Studies
ROC Curve
Reproducibility of Results
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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