Document Detail

Infant morbidity and mortality attributable to prenatal smoking in the U.S.
MedLine Citation:
PMID:  20547278     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although prenatal smoking continues to decline, it remains one of the most prevalent preventable causes of infant morbidity and mortality in the U.S. PURPOSE: The aim of this study was to estimate the proportion of preterm deliveries, term low birth weight deliveries, and infant deaths attributable to prenatal smoking. METHODS: Associations were estimated for prenatal smoking and preterm deliveries, term low birth weight (<2500 g) deliveries, sudden infant death syndrome (SIDS), and preterm-related deaths among 3,352,756 singleton, live births using the U.S. Linked Birth/Infant Death Data Set, 2002 birth cohort. The 2002 data set is the most recent, in which 49 states used the same standardized smoking-related question on the birth certificate. Logistic regression models estimated ORs of prenatal smoking for each outcome, and the prenatal smoking population attributable fraction was calculated for each outcome. RESULTS: Prenatal smoking (11.5% of all births) was significantly associated with very (AOR=1.5, 95% CI=1.4, 1.6); moderate (AOR=1.4, 95% CI=1.4, 1.4); and late (AOR=1.2, 95% CI=1.2, 1.3) preterm deliveries; term low birth weight deliveries (AOR=2.3, 95% CI=2.3, 2.5); SIDS (AOR=2.7, 95% CI=2.4, 3.0); and preterm-related deaths (AOR=1.5, 95% CI=1.4, 1.6). It was estimated that 5.3%-7.7% of preterm deliveries, 13.1%-19.0% of term low birth weight deliveries, 23.2%-33.6% of SIDS, and 5.0%-7.3% of preterm-related deaths were attributable to prenatal smoking. Assuming prenatal smoking rates continued to decline after 2002, these PAFs would be slightly lower for 2009 (4.4%-6.3% for preterm-related deaths, 20.2%-29.3% for SIDS deaths). CONCLUSIONS: Despite recent declines in the prenatal smoking prevalence, prenatal smoking continues to cause a substantial number of infant deaths in the U.S.
Patricia M Dietz; Lucinda J England; Carrie K Shapiro-Mendoza; Van T Tong; Sherry L Farr; William M Callaghan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of preventive medicine     Volume:  39     ISSN:  1873-2607     ISO Abbreviation:  Am J Prev Med     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8704773     Medline TA:  Am J Prev Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  45-52     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Inc.
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia 30341, USA.
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MeSH Terms
Gestational Age
Infant Mortality*
Infant, Low Birth Weight
Infant, Newborn
Logistic Models
Pregnancy Outcome
Premature Birth / etiology*
Smoking / adverse effects*,  epidemiology
Sudden Infant Death / etiology
United States / epidemiology
Young Adult

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