| Infant feeding in the second 6 months of life related to iron status: an observational study. | |
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MedLine Citation:
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PMID: 17537759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the relationship between iron status in infancy and type of milk and weaning solids consumed. DESIGN: An observational cohort study. SETTING: 928 term infants from the Avon Longitudinal Study of Parents and Children in 1993-94. METHODS: Haemoglobin and ferritin concentrations at 8 and 12 months were assessed in relation to type and quantity of milk intake at 8 months. RESULTS: By WHO criteria, 22.7% of the infants were anaemic at 8 months and 18.1% at 12 months. More breast--than formula-fed infants were anaemic at 8 and 12 months. Cows' milk as the main drink was associated with increased anaemia at 12 months and low ferritin at 8 and 12 months. No association was found between any nutrients and haemoglobin concentrations. Protein and non-haem iron intakes were positively associated with ferritin concentrations and calcium intake negatively. This effect was more marked in infants being fed cows' milk. More than 25% of infants in the breast milk and cows' milk groups and 41% of infants having >6 breast feeds per day had iron intakes below the lower reference nutrient intake. Feeding cows' milk or formula above 600 ml or >6 breast feeds per day was associated with lower intakes of solids. CONCLUSIONS: Both breast and cows' milk feeding were associated with higher levels of anaemia. Satisfactory iron intake from solids in later infancy is more likely if formula intake is <600 ml per day and breast feeds are limited to <6 feeds per day. Cows' milk should be strongly discouraged as a main drink before 12 months. |
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Authors:
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David Hopkins; Pauline Emmett; Colin Steer; Imogen Rogers; Sian Noble; Alan Emond |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-05-30 |
Journal Detail:
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Title: Archives of disease in childhood Volume: 92 ISSN: 1468-2044 ISO Abbreviation: Arch. Dis. Child. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-09-26 Completed Date: 2007-10-15 Revised Date: 2010-10-04 |
Medline Journal Info:
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Nlm Unique ID: 0372434 Medline TA: Arch Dis Child Country: England |
Other Details:
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Languages: eng Pagination: 850-4 Citation Subset: AIM; IM |
Affiliation:
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Bristol Children's Hospital, Bristol, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Iron-Deficiency
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diagnosis*,
prevention & control Animals Breast Feeding / adverse effects* Cohort Studies Female Ferritins Humans Infant Infant Formula / administration & dosage Infant Nutritional Physiological Phenomena Male Milk / adverse effects* Multivariate Analysis Nutritional Requirements |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
| Chemical | |
Reg. No./Substance:
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9007-73-2/Ferritins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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