| Infant botulism. | |
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MedLine Citation:
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PMID: 17314986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infant botulism results from the absorption of heat-labile neurotoxin produced in situ by ingested Clostridium botulinum. Honey and environmental exposure are the main sources of acquisition of the organism. Clinical manifestations are owing to progressive neuromuscular blockade, initially of muscles innervated by cranial nerves and later of the trunk, extremities and diaphragm. Presynaptic autonomic nerves are also affected. The diagnosis is made on clinical grounds and is confirmed by recovery of the organism or by detection of toxin in the stool. Management includes meticulous supportive intensive care that may include mechanical ventilation and administration of human botulinum immunoglobulin in severe cases. |
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Authors:
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I Brook |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 27 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-02-22 Completed Date: 2007-04-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 175-80 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Georgetown University School of Medicine, Washington, DC 20016, USA. IB6@georgetown.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Botulism / diagnosis*, epidemiology, etiology, prevention & control, therapy* Breast Feeding Clostridium botulinum / isolation & purification, physiology Diagnosis, Differential Humans Infant Infant Formula Nutritional Support Risk Factors Seasons Spores, Fungal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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