| INDUSTRIAL PENTACHLOROPHENOL POISONING IN WINNIPEG. | |
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MedLine Citation:
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PMID: 14259335 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Enquiry into the occupational history of a patient presenting with stupor, hyperpyrexia and profuse sweating, and dying at a Winnipeg hospital a few hours later in coma, finally led to the identification of pentachlorophenol-a substance widely used as a wood preservative-as the cause of death of this worker and the cause of non-fatal intoxication in four other workers engaged by wood-processing plants. In these latter four cases the prominent clinical symptoms were sweating, weight loss and gastrointestinal complaints. A review of the literature revealed that pentachlorophenol exerts its toxicity following cutaneous absorption or inhalation by interference with oxidative phosphorylation, resulting in excessive release of heat. This substance has been the cause of several deaths in other countries. Observance of simple precautionary measures that ensure adequate ventilation and skin protection should suffice in making this industrially useful product safe. |
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Authors:
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H BERGNER; P CONSTANTINIDIS; J H MARTIN |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian Medical Association journal Volume: 92 ISSN: 0008-4409 ISO Abbreviation: Can Med Assoc J Publication Date: 1965 Feb |
Date Detail:
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Created Date: 1965-05-01 Completed Date: 1996-12-01 Revised Date: 2011-09-28 |
Medline Journal Info:
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Nlm Unique ID: 0414110 Medline TA: Can Med Assoc J Country: CANADA |
Other Details:
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Languages: eng Pagination: 448-51 Citation Subset: OM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Canada Occupational Diseases* Occupational Medicine* Pharmacology* Phenols* Poisoning* Skin Absorption* Toxicology* |
| Chemical | |
Reg. No./Substance:
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0/Phenols |
| Comments/Corrections | |
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