| Induction of vaginal Lactobacillus phages by the cigarette smoke chemical benzo[a]pyrene diol epoxide. | |
| | |
MedLine Citation:
|
PMID: 10751726 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Because smoking increases a woman's risk of contracting bacterial vaginosis (BV), which is manifested by a reduction of vaginal lactobacilli and an overgrowth of anaerobic bacteria, chemicals contained in cigarette smoke were analyzed in vitro to determine their role in reducing lactobacilli. The result showed that trace amounts of benzo[a]pyrene diol epoxide (BPDE), which can be found in vaginal secretion of women who smoke, significantly increased phage induction in lactobacilli. This finding implies that smoking may reduce vaginal lactobacilli by promoting phage induction. |
| | |
Authors:
|
S I Pavlova; L Tao |
Related Documents
:
|
10782746 - Candida vaginitis: self-reported incidence and associated costs. 3540896 - Role of ureaplasma urealyticum in amnionitis. 21647176 - Xrcc1 arg399gln and arg194trp polymorphisms in prostate cancer risk: a meta-analysis. 17065846 - Associations between intravaginal practices and bacterial vaginosis in kenyan female se... 9373386 - Female circumcision among egyptian women. 8309566 - Sexual dysfunction in partial epilepsy: a deficit in physiologic sexual arousal. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Mutation research Volume: 466 ISSN: 0027-5107 ISO Abbreviation: Mutat. Res. Publication Date: 2000 Mar |
Date Detail:
|
Created Date: 2000-05-03 Completed Date: 2000-05-03 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0400763 Medline TA: Mutat Res Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 57-62 Citation Subset: IM |
Affiliation:
|
Department of Oral Biology, College of Dentistry, University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL 60612, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
/
adverse effects* Bacteriophages / drug effects*, growth & development Dose-Response Relationship, Drug Female Humans Lactobacillus / drug effects*, virology Lysogeny / drug effects Mutagens / adverse effects* Smoking / adverse effects* Vagina / microbiology* Vaginosis, Bacterial / chemically induced, microbiology |
| Chemical | |
Reg. No./Substance:
|
0/Mutagens; 55097-80-8/7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clastogenic effect of copper deficiency in cattle.
Next Document: Comet assay: rapid processing of multiple samples.