Document Detail


Induction of metallothionein and effect on essential metals in cadmium-loaded frog Xenopus laevis.
MedLine Citation:
PMID:  6133686     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Cadmium (Cd) was administered orally as metallothionein (MT) in food or intramuscularly as MT and Cd2+ into a frog Xenopus laevis. 2. Oral administration resulted in low accumulation of Cd without affecting essential metal levels. 3. Intramuscular administrations of Cd as MT and Cd2+ resulted in accumulation of Cd in the kidney and in the liver and kidney, respectively, by inducing a Cd-binding protein which has properties characteristic of MT.
Authors:
K T Suzuki; Y Tanaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology     Volume:  74     ISSN:  0742-8413     ISO Abbreviation:  Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol.     Publication Date:  1983  
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2007-07-23    
Medline Journal Info:
Nlm Unique ID:  8310013     Medline TA:  Comp Biochem Physiol C     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  311-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Animals
Cadmium / administration & dosage*,  metabolism
Female
Injections, Intramuscular
Kidney / metabolism
Liver / metabolism
Male
Metalloproteins / metabolism*
Metallothionein / metabolism*
Rabbits
Xenopus laevis
Chemical
Reg. No./Substance:
0/Metalloproteins; 7440-43-9/Cadmium; 9038-94-2/Metallothionein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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