| Induction of a local pseudo-pregnancy for the treatment of endometriosis. | |
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MedLine Citation:
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PMID: 19699590 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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As a common cause of chronic pelvic pain, endometriosis affects 10% of women of reproductive age. The most popular strategy for treating endometriosis is pseudo-pregnancy therapy. However, the efficacy of common systemic pseudo-pregnancy therapy is significantly attenuated by poor compliance because of so many side effects. While levonorgestrel-releasing intrauterine systems (LNG-IUS) successfully localize the effect of pseudo-pregnancy to the genital tract in treating endometriosis, it seemed to be insufficient to suppress the ovarian and extragenital endometriosis. We postulate that induction of a local pseudo-pregnancy via progestogen-loaded microsphere in the lesions of endometriosis may provide a more effective treatment with fewer side effects. |
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Authors:
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Peng Yuan; Yanhong Huang; Biliang Cheng; Jianfang Zhang; Xiaoyan Xin |
Publication Detail:
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Type: Journal Article Date: 2009-08-21 |
Journal Detail:
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Title: Medical hypotheses Volume: 74 ISSN: 1532-2777 ISO Abbreviation: Med. Hypotheses Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: United States |
Other Details:
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Languages: eng Pagination: 56-8 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Xijing Hospital, Fourth Military Medical University, No 17 Changle West Road, Xi'an, Shaan'xi 710032, China. ypfmmu@gmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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