Document Detail

Induction of labour by simultaneous intravenous administration of prostaglandin E 2 and oxytocin.
MedLine Citation:
PMID:  4569549     Owner:  NLM     Status:  MEDLINE    
In a group of 20 matched primigravid patients labour was induced by forewater amniotomy followed by intravenous oxytocin (Syntocinon) administered in escalating doses. Ten of these patients, in a double-blind trial, also received prostaglandin E(2) infused simultaneously with the oxytocin. In the combined prostaglandin-oxytocin group there was a noticeable reduction in the dosage of oxytocin required to produce effective uterine action, and the duration of labour was also reduced. No side effects were observed.
W C Naismith; W Barr; J MacVicar
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British medical journal     Volume:  4     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1972 Nov 
Date Detail:
Created Date:  1973-04-25     Completed Date:  1973-04-25     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  461-2     Citation Subset:  AIM; IM    
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MeSH Terms
Amnion / surgery
Clinical Trials as Topic
Drug Combinations
Infant, Newborn
Labor, Induced*
Oxytocin / administration & dosage*
Prostaglandins / administration & dosage*
Time Factors
Reg. No./Substance:
0/Drug Combinations; 0/Placebos; 0/Prostaglandins; 50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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