Document Detail


Induction of labor with vaginal misoprostol plus oxytocin versus oxytocin alone.
MedLine Citation:
PMID:  20347088     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare the effect of an oxytocin infusion alone or preceded by an intravaginal application of misoprostol for labor induction in women with term pregnancies and a low Bishop score. METHODS: This study randomized 100 multiparous women with singleton pregnancies over 38 weeks and a Bishop score less than 6 to receive either a single 50-microg dose of misoprostol intravaginally 3 hours before initiation of the oxytocin infusion or only an oxytocin infusion. The time from induction to delivery, the route of delivery, and maternal and fetal outcomes were analyzed. RESULTS: The mean time from induction to delivery was 9.36+/-1.97 hours in the misoprostol plus oxytocin group and 11.08+/-3.23 in the oxytocin alone group (P=0.002). The rates of vaginal delivery, 1- and 5-minute Agpar scores, placental abruption, and postpartum hemorrhage were similar between the 2 groups, as were the rates of admission to the neonatal intensive care unit. There were no cases of perinatal asphyxia. CONCLUSION: A 50-microg intravaginal application of misoprostol before starting the oxytocin infusion is a more effective method of labor induction than an oxytocin infusion alone for our study population.
Authors:
Osman Balci; Alaa S Mahmoud; Suna Ozdemir; Ali Acar
Related Documents :
7078898 - Treatment of premature labor with subcutaneous terbutaline.
15925438 - Fetal head position during the second stage of labor: comparison of digital vaginal exa...
16364008 - Evidence for interleukin-10-mediated inhibition of cyclo- oxygenase-2 expression and pr...
12011878 - Paracervical block for labor analgesia: a brief historic review.
8490098 - Endoscopic treatment of ectopic pregnancies.
9481548 - The fourth sound of korotkoff in pregnancy: a myth.
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2010-03-26
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  110     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-08-04     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  64-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Meram School of Medicine, Selcuk University, Konya, Turkey. drobalci@yahoo.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abruptio Placentae / epidemiology
Administration, Intravaginal
Adult
Apgar Score
Drug Therapy, Combination
Female
Humans
Infant, Newborn
Infusions, Intravenous
Labor, Induced / methods*
Misoprostol / administration & dosage,  therapeutic use*
Oxytocics / administration & dosage,  therapeutic use*
Oxytocin / administration & dosage,  therapeutic use*
Postpartum Hemorrhage / epidemiology
Pregnancy
Pregnancy Outcome
Time Factors
Chemical
Reg. No./Substance:
0/Oxytocics; 50-56-6/Oxytocin; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bone mineral density in women of a low socioeconomic level using DMPA for contraception in rural Upp...
Next Document:  Association between adolescent marriage and marital violence among young adult women in India.