| Induction of labor with oral misoprostol in nulliparous mothers of twins. | |
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MedLine Citation:
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PMID: 16519614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The efficacy and safety of oral misoprostol for labor induction of twins is unknown. We conducted a retrospective case-control study to evaluate the use of oral misoprostol in near term (> or =35 weeks) twin pregnancies in nulliparas. Eligible cases were given 100 mcg oral misoprostol, which was repeated after 6 h if labor did not start. Either a third dose or diluted oxytocin infusion were given in intractable cases. Diluted oxytocin infusion was used for augmentation. Controls were nulliparas delivered at > or =35 weeks by elective cesarean section. The two groups were comparable in most aspects, except for fetal malpresentation, which was the major reason for avoiding induction. Of the 69 patients in whom labor was induced, 53 (76.8%) had a vaginal birth, 3 (4.3%) had a combined twin delivery, and 13 (18.8%) had a cesarean during labor. The mean length of stay of the neonates was significantly shorter among study cases, without significant difference in the frequency of delayed discharges as an overall proxy for neonatal complications. Labor induction with oral misoprostol could be offered to patients in whom near term vaginal twin delivery is unequivocally permitted and wish to deliver by the vaginal route. |
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Authors:
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Teresinha Simões; Pedro Condeço; Elsa Dias; Paula Ventura; Cristina Matos; Isaac Blickstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of perinatal medicine Volume: 34 ISSN: 0300-5577 ISO Abbreviation: J Perinat Med Publication Date: 2006 |
Date Detail:
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Created Date: 2006-03-07 Completed Date: 2006-09-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0361031 Medline TA: J Perinat Med Country: Germany |
Other Details:
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Languages: eng Pagination: 111-4 Citation Subset: IM |
Affiliation:
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Department of Maternal-Fetal Medicine and Neonatology, Maternity Dr. Alfredo da Costa, Lisbon, Portugal. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Case-Control Studies Cesarean Section / statistics & numerical data Delivery, Obstetric / statistics & numerical data Female Humans Labor, Induced / methods* Misoprostol / administration & dosage*, adverse effects Oxytocics / administration & dosage*, adverse effects Parity Pregnancy Retrospective Studies Twins* |
| Chemical | |
Reg. No./Substance:
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0/Oxytocics; 59122-46-2/Misoprostol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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