Document Detail

Induction of labor with intravenous prostaglandin.
MedLine Citation:
PMID:  937389     Owner:  NLM     Status:  MEDLINE    
The present study utilizing an open label design evaluates the efficacy of prostaglandin F2alpha in the induction of labor in normal and complicated primigravid and multigravid pregnancies and in particular in patients with an unripe cervix. The results reveal that labor was successfully induced in 33 of 38 (86.8 per cent) normal patients in the 0 to 5 Bishop group and in 17 of 18 (94.4 per cent) in the 6 to 13 Bishop group. In the complicated pregnancies (abnormal group) 26 to 28 (84 per cent) in the 0 to 5 Bishop group and 13 of 13 (100 per cent) in the 6 to 13 Bishop group were successfully induced. There were two cesarean sections for obstetric indications. Hypertonus occurred only four times and responded to dose reduction. The most common problem--nausea and vomiting (29 per cent)--was easily controlled. Prostaglandin when judiciously used appears to be a safe drug for the induction of labor at term in normal as well as complicated pregnancies and in patients with low inducibility scores.
P Beck; M I Lilling
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  125     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-09-01     Completed Date:  1976-09-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  648-54     Citation Subset:  AIM; IM    
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MeSH Terms
Apgar Score
Infant, Newborn
Infusions, Parenteral
Labor, Induced*
Muscle Tonus
Pregnancy Complications
Prostaglandins F / administration & dosage*,  adverse effects,  pharmacology
Time Factors
Reg. No./Substance:
0/Prostaglandins F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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