| Induction of labor. A double-blind randomized controlled study of prostaglandin E2 vaginal suppositories compared with intranasal oxytocin and with sequential treatment. | |
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MedLine Citation:
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PMID: 3885670 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a double-blind randomized controlled study of 300 women, 150 primiparas and 150 multiparas, induction of labor by means of vaginal suppositories containing 3 mg prostaglandin E2 (PGE2) was compared with the conventional method of intranasal oxytocin and with a combined method of 3 mg PGE2 vaginal suppositories alternating with intranasal oxytocin. In the PGE2 group the intensity of delivery was significantly greater than in the oxytocin group, among both primiparas and multiparas and among the patients with ripe and unripe cervix. The efficiency of the combined treatment could no be evaluated because of the high intensity of delivery during the first 24 hours. There were no maternal side effects, and no significant difference in the frequencies of failed induction and cesarean section. |
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Authors:
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B Andreasson; J E Bock; J Larsen |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 64 ISSN: 0001-6349 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 1985 |
Date Detail:
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Created Date: 1985-05-13 Completed Date: 1985-05-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 157-61 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Intranasal Clinical Trials as Topic Dinoprostone Double-Blind Method Female Humans Infant, Newborn Labor, Induced* Oxytocin / administration & dosage* Parity Pregnancy Prostaglandins E / administration & dosage* Random Allocation Suppositories |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandins E; 0/Suppositories; 363-24-6/Dinoprostone; 50-56-6/Oxytocin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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